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Cutaneous Eruption - Rash

Overview, Causes, & Risk Factors

A rash is an area of the skin that has broken out or changed in appearance. It may affect one small patch of skin or the entire body.

What is going on in the body?

There are many skin changes that can occur with a rash, including:

  • swelling
  • warmth
  • blisters
  • bumps
  • color changes
  • itching
  • pain
  • Skin can react or break out for many different reasons, ranging from allergic reactions to infections and even cancer.

    What are the causes and risks of the condition?

    There are many possible causes of a rash. General categories include:

  • infections, such as ringworm; Borrelia burgdorferi. It is passed to humans through tick bites. ',CAPTION,'Lyme Disease');" onmouseout="return nd();">Lyme disease; Treponema pallidum bacteria. Less often, syphilis is transmitted from a pregnant woman to her baby. This form of syphilis is known as congenital syphilis. ',CAPTION,'Syphilis');" onmouseout="return nd();">syphilis; measles;chickenpox; scabies; roseola; impetigo; genital herpes and herpes zoster; Rocky Mountain spotted fever;Kawasaki disease;hand, foot, and mouth disease; Bartonella henselae. ',CAPTION,'CAT Scratch Disease');" onmouseout="return nd();">cat scratch disease; Group A strep infections; staphylococcus infections; diaper rash; and scarlet fever
  • allergic reactions, which can be from medications, metals, chemicals, soaps, lotions, foods, or other materials
  • primary skin diseases, such as acne, psoriasis, eczema, or rosacea, which often occur for unknown reasons
  • autoimmune disorders, such as systemic lupus erythematosus, scleroderma,, and ulcerative colitis
  • other conditions and diseases, such as diabetes or pregnancy
  • skin cancer or a cancer deeper in the body that causes a rash
  • leukemia, a blood cancer
  • inflammation of blood vessels, called vasculitis, in the skin
  • poor circulation, which commonly causes rashes in the lower legs
  • reaction to various childhood vaccinations, such as the chickenpox vaccine
  • heat or sun exposure
  • Other causes are also possible. Sometimes the cause is not found.


    Symptoms & Signs

    What are the signs and symptoms of the condition?

    There are many questions a healthcare provider may have when someone complains of a rash. For instance, he or she may ask:

  • how long the rash has been present
  • how the rash started and changed over time
  • whether or not the rash itches
  • whether or not the person has a fever or chills
  • whether anyone the person knows has had a similar rash
  • whether the person has any allergies
  • what medications the person is taking
  • whether the person has had similar or other rashes in the past
  • whether the person has had a recent insect or tick bite
  • The healthcare provider may ask about other symptoms, which can help narrow the list of possible causes. For instance, a person may be asked about his or her sexual history or whether he or she has had arthritis or weight loss.


    Diagnosis & Tests

    How is the condition diagnosed?

    The cause of some rashes can be diagnosed after a history and examination of the rash. Other rashes may be more difficult to identify. Further tests may be needed, including blood or urine tests. Sometimes, a biopsy of the affected skin is needed. This involves removing a small piece of skin with a special tool. The skin can then be analyzed in the lab to help determine the cause.

    Further tests may be needed in some cases, depending on the suspected cause. For instance, the provider may order a chest X-ray if he or she suspects that a lung infection is causing the rash.


    Prevention & Expectations

    What can be done to prevent the condition?

    Prevention of a rash depends on the cause, which is often difficult to diagnose. Those with allergies should avoid the substances they are allergic to whenever possible. Routine childhood vaccines can prevent some infections that cause a skin rash, such as measles and chickenpox. Avoiding the sun and using sunscreen can reduce the risk of skin cancer.

    What are the long-term effects of the condition?

    Some rashes, such as severe acne, may cause permanent scarring of the skin. Other rashes may become infected because of skin breakdown. In very rare cases, such as with severe allergic skin reactions, rashes can even result in death.

    For most rashes, the long-term effects are related to the underlying cause. For instance, cancer or serious infections that cause rashes may result in death. Rashes associated with pregnancy often go away after delivery and have no long-term effects.

    What are the risks to others?

    In some cases, a rash can be contagious and spread to others. In most cases, however, a rash poses no risk to others.


    Treatment & Monitoring

    What are the treatments for the condition?

    Affected skin should be kept clean, especially if there is skin breakdown. Specific treatment depends on the cause. For instance, those with infections may need antibiotic pills or creams applied to the rash. Those with allergic reactions may need antihistamines or corticosteroid pills or creams. Those with autoimmune disorders may need medications to suppress the immune system. Those with cancer or poor circulation may need surgery.

    What are the side effects of the treatments?

    Medications may cause allergic reactions, stomach upset, and headaches. Specific side effects depend on the medications used. For instance, antihistamines often cause drowsiness. Surgery may cause bleeding, infection, or allergic reaction to anesthesia.

    What happens after treatment for the condition?

    If the rash goes away, an individual may or may not need further treatment. For instance, those with diabetes or poor circulation need further treatment and monitoring even after their rashes go away. Those who have ringworm, a fungal infection of the skin, are cured after treatment. They can return to normal activities without further treatment.

    How is the condition monitored?

    People can monitor their own rashes at home. Those with skin breakdown need to watch for infection until the skin heals over. The provider may also want to monitor the rash periodically, depending on the cause. Any new or worsening symptoms should be reported to the healthcare provider.



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