i know that i have cvs, i am using tear drops, but still, water is coming from my eyes like anything, i feel real cold in eyes and then water comes out, why so, is there any homemade natural way to ...
I have taken all the allergy meds out there and I am still not doing so well this season. I have a raging headache (3 days now) and have sneezed so much its making me dilerious all this and I am on ...
I am having a hard time finding information on allergy related to exercise and how to treat them, although it is apparently not that uncommon.
For example, some people (including myself) ...
how long does minocycline stay in your system?
I am having an allergic reaction to minocycline and I've been taking it for 3 weeks. The hives come and go as I take antihysthamines. Im figuring the mino is still in my system. How long does it take to get rid of minocycline from your system?
Minocycline is rapidly absorbed after oral administration and absorption is not significantly impaired by ingestion of food or milk. After single oral doses of 150 mg in humans, minocycline yields serum levels that are generally 2 to 4 times higher than those of most other tetracyclines at all time intervals. When serum activity is determined against a standard of tetracycline, 150 mg of minocycline gives activity levels 16 or more times higher than 250 mg of tetracycline at 24 to 48 hours, this difference being largely due to the much longer serum half life of minocycline.
Minocycline is widely distributed in body tissues, with higher concentrations being found in cerebrospinal fluid and sputum than with other tetracycline analogues. As in blood, the concentration in tissues is generally 2 to 4 times higher with minocycline than with tetracycline.
Following a single dose of two 100 mg minocycline HCL capsules administered to ten normal adult volunteers, serum levels ranged from 0.74 to 4.45 mg/mL in one hour and attained peak levels between 2 and 3 hours; after 12 hours, they ranged from 0.34 to 2.36 mg/mL. Therapeutic levels are 1-2 mg/mL. The serum half life following a 200 mg dose in 12 normal volunteers ranged from 11 to 17 hours, in 7 patients with hepatic dysfunction ranged from 11 to 16 hours and in 5 patients with renal dysfunction ranged from 18 to 69 hours. Between 55% and 76% of an administered dose is bound by serum proteins.
Minocycline is excreted via the faeces primarily and via the urine at a low rate. High serum protein binding and the lipophylic properties contribute to this low excretion rate. The urinary and faecal recovery of minocycline when administered to 12 normal volunteers is one half to one third that of tetracycline.